ISSN 2736-1594
Research Article
International Journal of Obstetrics and Gynecology ISSN 2326-7234 Vol. 7 (9), pp. 001-007, September, 2019. © International Scholars Journals
Full length Research paper
A ten year clinical experience with intrauterine contraceptive device (IUCD) in a Nigerian tertiary health institution
Igwegbe A. O.*, Ugboaja J. O., and Monago E. N.
Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.
Accepted 17 April, 2019
Abstract
The prevalence of contraceptive use is still very low in Nigeria and the intrauterine contraceptive device (IUCD) is a common long term and reversible method of family planning. A ten year retrospective study of IUCD acceptors at the family planning clinic of Nnamdi Azikiwe University Teaching Hospital Nnewi was carried out. The socio-demographic characteristics, side effects/complications, duration of use, and reasons for discontinuation were analyzed. There were 861 IUCD acceptors among 1345 family planning clients giving the IUCD acceptance rate of 64.1%. Also 36.8% had used it previously. The mean age and number of living children were 30.7±5.7 years and 4.2±1.9, respectively. Both the mean age of the limiters (34.5 vs 29.0 years) and their number of living children (6.0 vs 3.5) were significantly higher than those for spacers (p = 0.00). Almost all the clients were married, majority (89.3%) had secondary and or tertiary education and 70.2% were spacers. The mean duration of use was 3.1±1.9 years. Most of the clients (82.4%) did not experience any side effect/complication. The common side effects/complications were vaginal discharge (7.7%), menorrhagia (1.9%), and missing IUCD (1.9%). In multivariate analysis the duration of use correlated positively with the number of living children (p = 0.00) while age had no effect on the duration of use (p = 0.025). Clients with secondary and or tertiary education reported side effects more than those with lesser level of education. The desire for pregnancy (36%) was the commonest reason for its discontinuation and the average discontinuation rate was 55.1%. The contraceptive prevalence in relation to the number of deliveries within the study period was low (12.4%) . There is great need to intensify motivation and health education on the availability and benefits of IUCD. Also provision of free commodity and services shall improve its utilization and promote maternal health.
Key words: Family planning, IUCD, utilization.
and Monago E. N., Igwegbe A. O.*, Ugboaja J. O.
https://doi.org/10.46882/IJOG/1063Research Article
International Journal of Obstetrics and Gynecology ISSN 2326-7234 Vol. 7 (8), pp. 001-004, August, 2019. © International Scholars Journals
Full Length Research Paper
The influence of mode of delivery on the levels of high-sensitivity C - reactive protein determined in umbilical cord blood
Aysem Kaya1, Güner Karatekin2*, Isıl Uzunhasan3 and Sami Hatıpo lu4
1Departmant of Biochemistry, Institute of Cardiology, Istanbul University, Istanbul, Turkey.
2Samsun Maternity and Childrens Hospital, Samsun, Turkey.
3Departmant of Cardiology, Institute of Cardiology, Istanbul University, Istanbul, Turkey.
4Department of Pediatrics, Sadi Konuk Bakirköy Education and Research Hospital, Istanbul, Turkey.
Accepted 23 March, 2019
Abstract
Data suggest that the fetus responds to chronic hypoxia by higher umbilical cord blood high-sensitive CRP concentrations. In order to evaluate the effects of acute hypoxia on fetus, cord blood high-sensitive CRP concentrations according to the delivery mode were compared. High-sensitive CRP concentration was measured by an immunonephelometric method in umbilical cord blood samples from 45 newborns born by different delivery modes (15 newborns by vaginal delivery, 15 newborns by elective cesarean section and 15 newborns by emergency section delivery due to acute hypoxia). No significant differences in high -sensitive CRP concentrations were documented between the three groups of newborns. However, a moderate negative correlation was determined between cord blood pH, pO2, and hs-CRP concentrations (p<0.05). In conclusion, the mode of delivery reflecting acute hypoxia did not influence cord blood high-sensitive CRP levels in newborns.
Key words: Inflammation, CRP, mode of delivery.
Isıl Uzunhasan and Sami Hatıpo lu, Aysem Kaya, Güner Karatekin*
https://doi.org/10.46882/IJOG/1062Research Article
Plasma lipids in Helicobacter pylori infected pregnant women
International Journal of Obstetrics and Gynecology ISSN 2326-7234 Vol. 7 (7), pp. 001-003, July, 2019. © International Scholars Journals
Short Communication
Plasma lipids in Helicobacter pylori infected pregnant women
Emmanuel Ike Ugwuja* and Nicholas C. Ugwu
Department of Chemical Pathology, Faculty of Clinical Medicine, Ebonyi State University, P.M.B. 053 Abakaliki, Nigeria.
Accepted 09 April, 2019
Abstract
Dyslipidaemia is a common feature of pregnancy and Helicobacter pylori infection respectively. We hypothesised that pregnant women infected with H . pylori may have increased disorder in lipid metabolism than non-infected pregnant women and thus estimated the plasma lipids in pregnant women with H. pylori infection. Forty (40) pregnant women (GA 11 weeks) attending ANC of the Department of Obstetrics and Gynaecology of the Federal Medical Centre, Abakaliki, Nigeria and found to be H. pylori positive by a serological test and 40 age- and socioeconomically matched H. pylori seronegative pregnant women who served as controls participated in this study. Fasting plasma lipids were determined by standard colorimetric methods. H. pylori infected pregnant women had significantly (p < 0.05) higher BMI than their non -infected counterparts. Although the total cholesterol, triglyceride and LDL-cholesterol were higher in H. pylori infected than non-infected pregnant women, only LDL-cholesterol was statistically significant (3.38 ± 1.52 vs. 2.34 ± 1.19, p = 0.001). On the other hand, HDL-cholesterol was lower in the H. pylori infected than non-infected pregnant women (0.68 ± 0.23 vs. 0.81 ± 0.49, p > 0.05). H. pylori infected than non-infected pregnant women exhibit greater disordered lipid metabolism that may be predisposing to increased risk for coronary heart disease (CHD). Further studies using larger sample sizes are needed to confirm these preliminary findings.
Key words: Helicobacter pylori, dyslipidaemia, pregnant women, coronary heart disease.
Emmanuel Ike Ugwuja*, Nicholas C. Ugwu
https://doi.org/10.46882/IJOG/1061Research Article
International Journal of Obstetrics and Gynecology ISSN 2326-7234 Vol. 7 (6), pp. 001-005, June, 2019. © International Scholars Journals
Full Length Research paper
Feasibility of a nested PCR for the diagnosis of vaginal trichomoniasis: study in Al-Madinah Al-Munwarrha, Saudi Arabia
Fawzia A. Habib1, Amany A. El-Aal2*, Nabeil S Yamany3, Ahmed M. mohamadein4, Omima Hamed4, Ahmed Bahashwan5, Nabeil Shehata5 and Lamia A. El-Hosseiny6
1Department of Obstetrics and Gynecology, Faculty of Medicine, Taibah University, Saudi Arabia.
2Department of Parasitology, Faculty of Medicine, Taibah University, Saudi Arabia.
3Department of Obstetrics and Gynecology, Maternity and Children's Hospital, Al-Madina Al-Munawarah, Saudi Arabia.
4Department of Biochemistry, Faculty of Medicine, Taibah University, Saudi Arabia.
5Laboratory of Obstetrics and Gynecology, Maternity and Children's Hospital, Al-Madina Al-Munawarah, Saudi Arabia.
6Department of Biomedical Technology, National Research Center, Cairo, Egypt.
Accepted 27 April, 2019
Abstract
In the present study, three vaginal swabs were collected from 1469 females clinically suspected of having Trichomonas vaginalis (T. v) infection. All samples were screened by both wet mount and Diamond's culture media that was considered as the golden standard in this study. T. vaginalis gene detection by nested PCR using 4 primers targeting the Tv-E650 gene was performed on the preserved vaginal uncultivated samples corresponding to the culture positive vaginal specimens plus 30 randomly selected samples equaled to those obtained negative culture results. The prevalence of T. vaginalis infection among our patients was calculated according to the results of the golden standard culture method to be 1.43% (21 out of 1469). Wet preparation was positive for only 13 samples and missed 8 samples. PCR diagnosed 20 samples and missed one specimen that became positive after 4 days of cultivation. In this study, PCR for trichomonads does not appear to offer a diagnostic advantage and its sensitivity did not exceed that of culture. Successful culture of T. vaginalis requires only the multiplication of a single organism, the same as that needed for PCR. Therefore, the present work is highly recommending the use of Diamond's culture in the diagnosis of trichomoniasis in women.
Key words: Trichomonas vaginalis, nested PCR, wet mount, diamond's culture, vaginal swabs, Saudi Arabia, Al-Madina Al-Munawarah.
Nabeil Shehata and Lamia A. El-Hosseiny, Omima Hamed, Ahmed M. mohamadein, Nabeil S Yamany, Ahmed Bahashwan, Amany A. El-Aal*, Fawzia A. Habib
https://doi.org/10.46882/IJOG/1060Research Article
Maternal serum leptin levels in severe preeclamptic pregnant women in early postpartum stage
International Journal of Obstetrics and Gynecology ISSN 2326-7234 Vol. 7 (5), pp. 001-006, May, 2019. © International Scholars Journals
Full length Research paper
Maternal serum leptin levels in severe preeclamptic pregnant women in early postpartum stage
Safiye Akansu Saylik1, Ismet Alki2*, Nebahat Bayram3, Volkan Tuna4, Nilufer Imamoglu5 and Yavuz Ceylan6
1Guven Hospital, Obstetric and Gynecology Department, Van, Turkey.
2Medical Park Hospital, Obstetric and Gynecology Department, Van, Turkey.
3Trabzon Maternity and Woman's and Children's Diseases Hospital, Trabzon, Turkey.
4Nizip Government Hospital, Obstetric and Gynecology Department, Nizip, Turkey.
5Hayat Hospital, Obstetric and Gynecology Department, Malatya, Turkey.
6Bakirkoy Maternity and Woman's and Children's Diseases Education Hospital, stanbul, Turkey.
Accepted 03 January, 2019
Abstract
The aim of this study is to determine early postpartum maternal serum leptin levels in severe preeclamptic pregnant women. This study was planned as a prospective controlled trial. The patient and control groups in the study were composed in the period between January 2003 and January 2004. The study, performed in the Department of Perinatology of SSK Bakirkoy Maternal Hospital and Women and Child Diseases Education Hospital, consists of forty-four singleton pregnant women giving birth after hospitalized with diagnosis of severe preeclampsia and forty-four normotensive singleton pregnant women who were found to have healthy pregnancy on examination and analysis before given birth. The venous blood of all pregnants was taken from the antecubital region in early postpartum period while they were all hungry. We studied the relation between demographic data, biochemical data, baby weight at birth and the serum leptin levels. Comparing the preeclamptic pregnant women with control group in terms of leptin, although leptin levels in severe preeclamptic pregnant women were found to be higher than control group, statistically, no significant difference was determined (p: 0.069). In severe preeclamptic group, baby weight at birth was found to be significantly lower (p: 0.000). Evaluating all pregnant women, it was determined that there has been a positive significant relation between serum leptin levels and diastolic tension (p: 0.044), urea (p: 0.019), creatinine (p:0.000), uric acid (p: 0.000); and a negative significant relation between serum leptin levels and baby weight at birth (p: 0.038). No relation was found between the leptin level and the gender of infants. No significant difference of early postpartum maternal serum leptin levels between severe preeclamptic group and normotensive group was determined.
Key words: Preeclampsia, early postpartum stage, serum leptin levels, severe preeclamptic pregnant women.
Ismet Alki*, Nilufer Imamoglu and Yavuz Ceylan, Safiye Akansu Saylik, Volkan Tuna, Nebahat Bayram
https://doi.org/10.46882/IJOG/1059Research Article
International Journal of Obstetrics and Gynecology ISSN 2326-7234 Vol. 7 (4), pp. 001-006, April, 2019. © International Scholars Journals
Full Length Research Paper
Immune-diagnosis of latent toxoplasmosis in childbearing age women in rural areas in EL Geizera State, Sudan
Khalil Mohamed1, Intisar EL Rayah2*, Alia Bilal2, EL Taib Gumaa2, Ali Abdel Magid3, Marek Maly4 and Petr Kodym5
1Commission for Biotechnology and Genetic Engineering, Department of Medical Biotechnology, Khartoum, Sudan.
2Tropical Medicine Research Institute TMRI, Khartoum, Sudan.
3Ministry of Science and Technology, Sudan.
4National Institute of Public Health, Department of Biostatistics and Informatics, Prague, Czech Republic.
5National Institute of Public Health, National Reference Laboratory for Toxoplasmosis, Prague, Czech Republic.
Accepted 08 January, 2019
Abstract
The current study is aimed to evaluate the prevalence rate of latent toxoplasmosis among childbearing women in rural areas in EL Geizera State. A total of 255 plasma samples were collected from two villages; AL Nuba and EL Massoudia in EL Geizera State, Sudan. and tested for Toxop-lasma gondii antibodies using three different screening tests (Latex Agglutination Test LAT,-Enzyme Link Immunosorbent Assay IgG, and Complement Fixation test (CFT) and one standard technique (Indirect Immunofluorescent Test (IIFT). The overall seroprevalence rate in the two villages was found 73.1%, using the standard method (IIFT). The prevalence rate was 60.7% in EL Nuba and 87.3% in EL Massoudia. The seroprevalence rate were found to be 62.3, 73.1, and 72.3% using the other three screening tests LAT, ELISA IgG, and CFT respectively. The prevalence rate was found increasing with age (p<0.001). Infection rate was higher in EL Massoudia village (p<0.001). This study indicated that there is a considerable rate of Toxoplasma infection among rural women and supported the concern that rural women in Sudan may be vulnerable to that infection.
Key words: Prevalence, Toxoplasma, Childbearing, Sudan.
Alia Bilal, Marek Maly and Petr Kodym, Intisar EL Rayah*, Ali Abdel Magid, EL Taib Gumaa, Khalil Mohamed
https://doi.org/10.46882/IJOG/1058