ISSN 2736-1594
International Journal of Obstetrics and Gynecology ISSN 2326-7234 Vol. 7 (4), pp. 001-006, April, 2019. © International Scholars Journals
Full Length Research Paper
Immune-diagnosis of latent toxoplasmosis in childbearing age women in rural areas in EL Geizera State, Sudan
Khalil Mohamed1, Intisar EL Rayah2*, Alia Bilal2, EL Taib Gumaa2, Ali Abdel Magid3, Marek Maly4 and Petr Kodym5
1Commission for Biotechnology and Genetic Engineering, Department of Medical Biotechnology, Khartoum, Sudan.
2Tropical Medicine Research Institute TMRI, Khartoum, Sudan.
3Ministry of Science and Technology, Sudan.
4National Institute of Public Health, Department of Biostatistics and Informatics, Prague, Czech Republic.
5National Institute of Public Health, National Reference Laboratory for Toxoplasmosis, Prague, Czech Republic.
Accepted 08 January, 2019
Abstract
The current study is aimed to evaluate the prevalence rate of latent toxoplasmosis among childbearing women in rural areas in EL Geizera State. A total of 255 plasma samples were collected from two villages; AL Nuba and EL Massoudia in EL Geizera State, Sudan. and tested for Toxop-lasma gondii antibodies using three different screening tests (Latex Agglutination Test LAT,-Enzyme Link Immunosorbent Assay IgG, and Complement Fixation test (CFT) and one standard technique (Indirect Immunofluorescent Test (IIFT). The overall seroprevalence rate in the two villages was found 73.1%, using the standard method (IIFT). The prevalence rate was 60.7% in EL Nuba and 87.3% in EL Massoudia. The seroprevalence rate were found to be 62.3, 73.1, and 72.3% using the other three screening tests LAT, ELISA IgG, and CFT respectively. The prevalence rate was found increasing with age (p<0.001). Infection rate was higher in EL Massoudia village (p<0.001). This study indicated that there is a considerable rate of Toxoplasma infection among rural women and supported the concern that rural women in Sudan may be vulnerable to that infection.
Key words: Prevalence, Toxoplasma, Childbearing, Sudan.