ISSN 2736-1594
International Journal of Obstetrics and Gynecology ISSN 2326-7234 Vol. 7 (8), pp. 001-004, August, 2019. © International Scholars Journals
Full Length Research Paper
The influence of mode of delivery on the levels of high-sensitivity C - reactive protein determined in umbilical cord blood
Aysem Kaya1, Güner Karatekin2*, Isıl Uzunhasan3 and Sami Hatıpo lu4
1Departmant of Biochemistry, Institute of Cardiology, Istanbul University, Istanbul, Turkey.
2Samsun Maternity and Childrens Hospital, Samsun, Turkey.
3Departmant of Cardiology, Institute of Cardiology, Istanbul University, Istanbul, Turkey.
4Department of Pediatrics, Sadi Konuk Bakirköy Education and Research Hospital, Istanbul, Turkey.
Accepted 23 March, 2019
Abstract
Data suggest that the fetus responds to chronic hypoxia by higher umbilical cord blood high-sensitive CRP concentrations. In order to evaluate the effects of acute hypoxia on fetus, cord blood high-sensitive CRP concentrations according to the delivery mode were compared. High-sensitive CRP concentration was measured by an immunonephelometric method in umbilical cord blood samples from 45 newborns born by different delivery modes (15 newborns by vaginal delivery, 15 newborns by elective cesarean section and 15 newborns by emergency section delivery due to acute hypoxia). No significant differences in high -sensitive CRP concentrations were documented between the three groups of newborns. However, a moderate negative correlation was determined between cord blood pH, pO2, and hs-CRP concentrations (p<0.05). In conclusion, the mode of delivery reflecting acute hypoxia did not influence cord blood high-sensitive CRP levels in newborns.
Key words: Inflammation, CRP, mode of delivery.