ISSN 2375-1177
African Journal of Agriculture and Food Security ISSN: 2375-1177 Vol. 12 (5), pp. 001-006, May, 2024. Available online at www.internationalscholarsjournals.org © International Scholars Journals
Full Length Research paper
Exploring the Persistence of Fish Allergies: The Role of Parvalbumin
Syed Hasan Arif * and Absar-ul Hasnain
Genetics Section, Department of Zoology, Faculty of Life Sciences, Aligarh Muslim University,
Aligarh-202002, UP, India.
Accepted 5 February, 2024
Abstract
Parvalbumins (PVs) form a major part of the fish skeletal muscle sarcoplasm, and were identified as the major cross-reactive allergens in a variety of fish species. Therefore, the intake of fish or fish-linked products may cause serious clinical problems. It is known that the biochemical and structural characteristics of a protein play a central role in determining its potential functions. This study is sought to evaluate the stability of PV’s structure which would be the foremost reasons in keeping them responsive yet after cooking. Here, PVs obtained from a commonly consumed fish Channa marulius were used as the test protein. The protein, PV turned out to be fairly resistant to high temperatures (90°C) and set on in a typical single band of 10 kD in SDS-PAGE. This suggests that following heating only partial and /or reversible loss of PV structure occurred, which rendered it allergenic to predisposed individuals.
Key words: Parvalbumin, allergen, stability, fish.