ISSN 2736-1756
Advanced Journal of Microbiology Research ISSN 2736-1756 Vol. 14 (6), pp. 001-005, June, 2020. © International Scholars Journals
Full Length Research Paper
A surveillance study of antimicrobial susceptibility in 11 hospitals in Kurdistan Province
Ahsan B.1, Beiranvand S.2, Abdulmaleki N.,3 Mohamadi H.4 and Kalantar E.5*
1Deputy of Treatment, Kurdistan University of Medical Sciences, Sanandja, Iran.
2Deputy of Food and Druh, Kurdistan University of Medical Sciences, Sanandja, Iran.
3Reference Laboratory, Kurdistan University of Medical Sciences, Sanandja, Iran.
4Mohammadi H, Evaluation Unit, Deputy of Treatment, Kurdistan University of Medical Sciences, Sanandja, Iran.
5Department of Microbiology, School of Medicine, Kurdistan University of Medical Sciences, Sanandja, Iran.
Accepted 10 May, 2020
Abstract
Antimicrobial resistance has become a serious public health concern all over the world. The objective of this study was to determine susceptibility patterns of microorganisms to antibiotics in 11 hospital laboratories in Kurdistan province. During one month period (February, 2010), all the clinical specimens which were received from the laboratories were processed for isolation and identification of bacteria to the species level by standard methods. Testing procedures were validated following the Kirby-Bauer disc diffusion technique using Muller Hinton agar. Susceptibility testing was performed on Mueller– Hinton agar. A total of 4395 clinical specimens were obtained from 4301 patients among them, 1062 (24.7%) were male and 3239 (75.3%) were female, giving on overall male to female ratio of 0.32. Their mean age was 31.3 years (range: 4 to 74 years). Based on data 310 pathogens were isolated and Escherichia coli 183 (59.3%), followed Klebsiella pneumoniae 40 (01.29%) and Staphylococcus aureus 39 (1.25%) were the predominant isolated bacteria. The most resistant antibiotics tested against isolated bacteria were penicillin, ampicillin, and amoxicillin. Lastly, these resistance rates leave imipenem and ciprofoxcacin as the reliable agent for the empirical treatment in this province. The present study has shown that the urinary tract infection (UTI) patients have a higher rate of infection. The risk of antibiotic resistance in isolated bacteria, particularly E. coli, emphasizes the importance of hospital control measures and rational prescribing policies. Lastly, these resistance rates leave ciprofloxcacin and imipenem as the reliable agent for the empirical treatment in this province.
Key words: Antimicrobial resistance, Escherichia coli, ciprofloxacin and imipenem.