ISSN 2167-0404
International Journal of Medicine and Medical Sciences ISSN 2167-0404 Vol. 5 (7), pp. 245-246, August, 2015. © International Scholars Journals
Full Length Research Paper
A study of prevalence of prostatic cancer among forensic autopsy cases
*Kam C.W, Saich T.A and Tien S.O
Department of Clinical Oncology, The Chinese University of Hong Kong, Shatin, Hong Kong. E-mail: [email protected].
Department of Hepatobiliary Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China.
Accepted 27 January, 2015
Abstract
In the aging society, elderly people often suffer cancer, which is associated with increased rates of fractures due to osteoporosis from cancer. In the present study, the prevalence of prostatic cancer, so-called “latent adenocarcinoma”, is investigated among forensic autopsy cases. Retrospective histo-pathology was performed on 114 subjects (61.8 ± 13.3 years old). Forth-four specimens (38.6%) harbored carcinomas with Gleason combined scores ranging from 3 to 9. The detection rate increased in accordance with age, in which the highest rate (8/13, 61.5%) was evident in the group of ≥ 80 years of age. However, no significant associations were apparent to age (P = 0.13) or body mass index (P = 0.36). Majority (34, 77.2%) displayed solitary lesions that were located mainly in the peripheral zone. Advanced capsular invasion was evident in five cases. The prostate that is not familiar to forensic pathologists should be examined in extrinsic fractures of the elderly because cancer might affect injury severity.
Key words: Forensic pathology, prostate, gleason score, histopathology, elderly.