Advances in Aquaculture and Fisheries Management

Advances in Aquaculture and Fisheries Management ISSN: 9424-2933 Vol. 5 (11), pp. 001-005, November, 2017. © International Scholars Journals

Full Length Research Paper

Studies on the hepatic antioxidant defense system in λ cyhalothrin-induced oxidative stress in fresh water tilapia (OREOCHROMIS  MOSSAMBICUS)

Rekha Parthasarathy* and John Joseph

Department of Zoology, Sacred Heart College, Thevara- Ernakulam Kerala, India.

Accepted 11 May, 2017

Abstract

The present study was undertaken to determine the effects of λ cyhalothrin-induced oxidative stress in fresh water tilapia (OREOCHROMIS MOSSAMBICUS) with respect to changes in the levels of lipid peroxidation [LPO], reduced glutathione [GSH], glutathione-dependent antioxidant enzymes (glutathione peroxidase [GPX] and glutathione-S-transferase [GST]) and antiperoxidative enzymes (catalase [CAT] and superoxide dismutase [SOD]). Significant (P<0.05) elevation in the level of lipid peroxidation was observed in λ cyhalothrin-intoxicated fishes as compared to controls. A concomitant (P<0.05) decline in hepatic antioxidant status was also observed. The results of the present investigation have indicated that the tissue antioxidant defense system is operating at a lower rate despite increased λ cyhalothrin-induced oxidative stress.

Key words: Antioxidant status, λ cyhalothrin, lipid peroxidation, Oreochromis mossambicus, oxidative stress, synthetic pyrethroid.