ISSN 2756-3332
African Journal of Nursing and Midwifery ISSN 2198-4638 Vol. 7 (12), pp. 001-004, December, 2019. © International Scholars Journals
Full Length Research Paper
Evaluation of leucocyte and its subgroups in iron deficiency anemia
Ali Özcan1, Muzaffer Çakmak2, Ahmet Ruhi Toraman3, Aslıhan Çolak2, Hamza Yazgan4, Mehmet Demirdöven4, Osman Yoku2 and Ahmet Gürel5*
1Biochemistry Laboratory of Private Central Hospital, Istanbul, Turkey.
2Outpatient Clinics of Internal Medicine of Private Sema Hospital, Istanbul, Turkey.
3Health Services of Private Sema Hospital, Istanbul, Turkey.
4Pediatric Clinics of Private Sema Hospital, Istanbul, Turkey.
5Biochemistry Laboratory of Private Sema Hospital, Istanbul, Turkey.
Accepted 10 May, 2019
Abstract
In this study, leukocyte, granulocyte, lymphocyte and monocyte count was evaluated in patients with iron deficiency anaemia. Complete blood count data from 84 patients (with iron deficiency anaemia) admitted to our hospital’s paediatrics and general medicine outpatient clinics, and 109 age- and sex-matched healthy controls, were evaluated retrospectively. Complete blood count analyses were performed with Micros 60, and serum iron and ferritin levels analyses were performed by auto analyzers. Whilst granulocyte count was higher in the group with iron deficiency anaemia, lymphocyte count was lower. No difference in monocyte count was found between the groups. Although total leukocyte count was higher in the group with anaemia, the difference was statistically insignificant. In anaemia, iron deficiency increases granulocyte but reduces lymphocyte count. The molecular basis of this dual effect of iron on cellular defence system is still, to a great extent, unexplained.
Key words: Iron deficiency anaemia, leucocyte, granulocyte, lymphocyte, monocyte.