Advanced Journal of Microbiology Research

ISSN 2736-1756

Advanced Journal of Microbiology Research Vol. 2015

Available online at http://internationalscholarsjournals.org/journal/ajmr

© 2015 International Scholars Journals

Full Length Research Paper

Antagonistic activity of a novel antibiotic against Mycobacterium tuberculosis

Chen-Xiaoxi and Yue Jun*

Basic Medicine College, Zhejiang Chinese Medicine University Binjiang District, Hangzhou City, Zhejiang Province, 310053, P. R. China.

Accepted 20 January, 2014

Abstract

The antibiotic produced by a newly isolated Bacillus subtilis has potent anti-tubercular activity against sixteen strains of Mycobacterium tuberculosis, most of which belong to MDR strains. MICs for the sixteen strains were evaluated. A series of spectrum analysis and element analysis determined that the antibiotic’s molecular formula was C27H46O2.

Key words: Bacillus subtilis, antibiotic, MIC, serum, anti-tubercular.