ISSN 2169-3048
International Journal of Biochemistry and Biotechnology ISSN 2169-3048 Vol. 6 (4), pp. 750-755, April, 2017. © International Scholars Journals
Full Length Research Paper
A study of serum electrolytes and calcium status in both hemodialysed and conservatively treated chronic kidney disease patients attending a tertiary care hospital of Assam
1Rashmi Rekha phukan and 2Rohini Kt. Goswami
1Department of Biochemistry, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India.
2Department of Biochemistry, Assam Medical College, Dibrugarh, Assam, India.
*Corresponding author E-mail: [email protected]
Accepted 15 November, 2016
Abstract
The present study is a hospital based study in patients with CKD attending a tertiary care hospital in assam. 71 CKD patients (31 conservatively treated and 40 hemodialysed) and 50 healthy controls were included in the study. Serum Na+ and calcium was significantly lower with p value 0.015 and <0.001 respectively in CKD groups as compared to the controls. The difference of serum potassium between the cases and controls was statistically not significant. Varied ranges of dyselectrolemia is observed in the CKD group with incidence of hyponatremia and hypokalemia being more prevalent in CKD patients undergoing treatment with prevalence of 28.1% and 53.5% respectively. Whereas prevalence of hypernatremia and hyperkalemia was found to be 12.6% and 11.2% respectively. Between the conservatively treated and hemodialysed group, hyponatremia was found to be more prevalent in conservatively treated group with prevalence of 41.9%, whereas hypokalemia was more prevalent in the hemodialysed group with prevalence of 60%. Hypocalcemia was prominent invariably in both conservative and hemodialysed group. There was significant difference of Na+ and K+ values between CKD patients treated by hemodialysis and conservatively with p values 0.0103 and 0.0258 respectively. Whereas there was no differences found for calcium between the two groups. Varied range of dyelectrolemia has been noticed in CKD patients that depend upon the mode of treatment.
Keywords: CKD, hemodialysis, dyselectrolemia, prevalence.