ISSN 2756-3707
International Journal of Histology and Cytology ISSN 2756-3707 Vol. 9 (6), pp. 001-006, June, 2022. © International Scholars Journals
Full Length Research Paper
Effects of extensive consumption of hot red pepper fruit on liver of rabbit
Mohamed A. Dkhil1,2* and Saleh Al-Quraishy2
1Department of Zoology and Entomology, Faculty of Science, Helwan University, Egypt.
2Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Accepted 1 May, 2022
Abstract
In the present study, we examined the effects of hot red pepper on rabbit’s hepatic tissue. Rabbits were orally ingested 2 g/Kg hot red pepper every day for 10 days. Hot red pepper induced a significant increase in temperature of rabbits after oral ingestion of each dose. Hepatic tissue damage was recorded through examination of the stained paraffin embedded sections. Inflammatory cellular infiltration and hepatocytic vacuolation were marked in rabbits ingested with the hot red pepper. Histochemical studies reveal a decrease in both of carbohydrates and protein contents in the liver. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), cholesterol, triglycerides and glucose were decreased in rabbit due to oral ingestion of hot red pepper. These scientific evidences show that hot red pepper possesses some chemical and pharmacological properties which are capable of inducing liver damage. Therefore, based on the findings of this study, the excessive consumption of red pepper is capable of inducing liver damage and so should be avoided.
Key words: Red pepper, rabbit liver, histology, biochemistry.