ISSN 2736-1756
Advanced Journal of Microbiology Research Vol. 2016
Available online at http://internationalscholarsjournals.org/journal/ajmr
© 2016 International Scholars Journals
Full Length Research Paper
Rationalizing some medicinal plants used in treatment of skin diseases
1Adebayo-Tayo B.C, 2,3Adegoke A.A, 2,*Okoh, A.I and 4Ajibesin K.K
1Department of Botany and Microbiology, University of Ibadan, Ibadan, Oyo State, Nigeria
2Applied and Environmental Microbiology Research Group (AEMREG),Department of Biochemistry and Microbiology, Plant Science Building, University of Fort Hare,Private Bag X1314, Alice 5700, South Africa
3Department of Microbiology, University of Uyo, Uyo, Akwa Ibom State, Nigeria 4Ogun State University, Ago-Iwoye, Ogun State, Nigeria.
Accepted 11 June, 2015
Abstract
The hydroethanolic extracts obtained from ten plant species being used as components of skin disease remedy in Southwest Nigeria were subjected to phytochemical analysis and screened for antimicrobial activity. The antimicrobial activity was determined against Escherichia coli NCIB 86, Staphylococcus aureus NCIB 8588, Klebsiella pneumoniae NCIB 418, Pseudomonas aeruginosa NCIB 950, Proteus vulgaris NCIB 67, Bacillus subtilis NCIB 3610, Candida albicans and Aspergillus flavus by agar diffusion method. Terpenes, flavonoids, tannins and saponin were detected in the active plants through phytochemical screening and confirmed by thin layer chromatography (TLC) . The plant extracts demonstrated antimicrobial effect against bacteria and the fungal cultures used in this study at different levels. The plant species Funtumia elastica, Raphyostylis beninensis, Butyrospermum paradoxum, Serataria caudula, Parkia biglobosa and Curculigo pilosa showed significant antimicrobial activities against the test organisms. Curculigo pilosa, F. elastic and P. biglobosa gave the highest zone of inhibition of 30 mm at 80 mg/ml against Aspergillus flavus, Bacilus subtilis and Proteus vulgaris while Curculigo pilosa also gave the least zone of inhibition of 2 mm at 80 mg/ml against Klebsiella pneumoniae. This relative high active index explains the antimicrobial effects of the remedy for skin diseases.
Key words: Phytochemical analysis, antimicrobial activity, TLC, skin disease, Funtumia elastica.