ISSN 2756-3340
African Journal of Infectious Diseases Research ISSN 2756-3340 Vol. 8 (6), pp. 001-002, June, 2021. © International Scholars Journals
Short Communication
Glycyrrhizin therapy for viral infections
Kei Numazaki
Department of Pediatrics, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido, 060-8543, Japan. Tel: (011) 611-2111 EXT.3413, Fax: (011) 611-0352, E-mail: [email protected].
Accepted 26 May, 2021
Abstract
Glycyrrhizin (GL) was reported as the most active in inhibiting replication of the severe acute respiratory syndrome (SARS)-associated coronavirus. Therapeutic effect of GL for liver dysfunction associated with cytomegalovirus (CMV) infection in immunocompetent individuals was evaluated. Liver dysfunction in 4 cases improved and CMV disappeared from urinary samples after administration of GL intravenously by the age of 12 months. GL treatment also should be applied for the patients with SARS.
Key words: Glycyrrhizin, SARS, cytomegalovirus.