ISSN 2375-1266
African Journal of Environmental and Waste Management ISSN 2375-1266 Vol. 9 (4), pp. 001-003, April, 2022. © International Scholars Journals
Short Communication
Antibacterial activity study of a mucoadhesive suspension containing ciprofloxacin
Subhashree Sahoo1*, Chandra Kanti Chakraborti1 and Subash Chandra Mishra2
1Kanak Manjari Institute of Pharmaceutical Sciences, Chhend, Rourkela-769015 Orissa, India.
2Department of Metallurgical and Materials Engineering, National Institute of Technology, Rourkela- 769008, Orissa, India.
Accepted 21 November, 2021
Abstract
Considering various effects of mucoadhesive suspension containing Ciprofloxacin, it was found that newly designed mucoadhesive formulation was better than its conventional immediate release preparation. Due to that their in vitro antibacterial activity was also studied and compared. It was found that the newly designed mucoadhesive formulation showed much larger zones of inhibition against all the strains used in the study than the conventional immediate release preparation. In addition, this novel formulation and even the standard discs of Ciprofloxacin produced more or less similar zones of inhibition. However, the conventional immediate release preparation was much inferior to the standard discs as far as the zones of inhibition were concerned.
Key words: Ciprofloxacin, mucoadhesive formulation, conventional immediate release preparation, antibacterial activity.