ISSN 2169-3048
International Journal of Biochemistry and Biotechnology ISSN 2169-3048 Vol. 8 (2), pp. 001-004, February, 2019. © International Scholars Journals
Full Length Research Paper
No xenotropic murine leukemia infection related infection (XMRV) discovered in Swedish monozygotic twins grating for chronic fatigue
*Gustavus Roy, Mikael Carl Anderson, and Larson Steig
Department of Cell and Molecular Biology, Science for Life Laboratory, University of Gothenburg, Gothenburg, Sweden.
Accepted 25 November, 2018
Abstract
The recent debate regarding the possible involvement of xenotropic murine leukemia virus-related virus (XMRV) in chronic fatigue syndrome (CFS) in humans has been intense due to the conflicting results from different studies and the unclear origin of the XMRV virus. In this study, we have addressed this issue by screening 47 pairs of monozygotic twins discordant for CFS using a sensitive PCR assay. The results are clearly negative for all samples. This is consistent with studies showing no evidence for the involvement of XMRV in CFS and supports the possibility that previous positive studies could be caused by laboratory artifacts.
Key words: Chronic fatigue syndrome (CFS), idiopathic chronic fatigue, infectious disease, xenotropic murine leukemia virus-related virus (XMRV), monozygotic twins.