ISSN 2736-1756
Advanced Journal of Microbiology Research Vol. 2016
Available online at http://internationalscholarsjournals.org/journal/ajmr
© 2016 International Scholars Journals
Full Length Research Paper
Antibiotic sensitivity of human genital mycoplasmas
Jafar Khan1*, Robeena Farzand1 and Pir Bux Ghumro2
1Department of Microbiology, Kohat University of Science and Technology Kohat, 26000, NWFP, Pakistan.
2Department of Microbiology, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Accepted 24 February, 2016
Abstract
The therapeutic failure of antimycoplasma drugs, subject to resistance is vital for specific microbiological investigation to overcome urogenital diseases among women. The susceptibility of 5 Mycoplasma hominis strains and 11 strains of Ureaplasma urealyticum were studied against six antibiotics namely: minocycline, lincomycin, erythromycin, tetracycline, doxycycline and rosaramicin. Both M. hominis and Ureaplasmas strains were highly resistant to tetracycline. It was observed that both rosaramicin and minocycline were active growth inhibitors for Ureaplasmas. However, erythromycin and lincomycin showed differential growth inhibitory patterns for M. hominis and Ureaplasma strains. In comparison, the minocycline and doxycycline exhibited similar antibiotic activity against Ureaplasma and M. hominis. The in vitro antibiotic sensitivity analysis for rosaramicin and erythromycin was also noted to be at the same level for all the isolates.
Key words: Mycoplasma hominis, Ureaplasma urealyticum, antibiotic sensitivity, drug resistance.