ISSN 2169-3048
International Journal of Biochemistry and Biotechnology ISSN 2169-3048 Vol. 14 (2), pp. 001-011, February, 2025. Available online at www.internationalscholarsjournals.org © International Scholars Journals
Full Length Research Paper
Investigating Charge-Transfer Complexes: Spectroscopic and Thermal Kinetic Analysis of (Panto & Ome)-prazole as Donor with DDQ, CHLC, and Iodine as Acceptors
Doa'a Fawzi Ba'amer1, Elsayed El-Mossalamy2, Laila Mohammad Al-Harbi1*, Abdullah Yousif Obaid1
1Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 42805 Jeddah 21551 Saudi Arabia.
2Department of Chemistry, Faculty of Science, Benha University, Benha, Egypt.
Accepted 10 October, 2013
Abstract
Charge transfer (CT) complexes were carried out using the most widely selling and effective pharmaceutical drugs as Pantoprazole (PANT) and Omeprazole (OMER) as electron donors; solid interaction with different benzoquinone derivatives as acceptors and Iodine were isolated and characterized by IR and 1H-NMR (Nuclear magnetic resonance) .Thermo gravimetric analysis with different heating rates (TGA) were studied on solid state complexes using computational integral methods for Coats Redfern and Ozawa using various solid state kinetic reaction models and established activation energy, energy band gape and thermodynamic parameters . The Differential Scanning Calorimetric (DSC) technique was used to study the nature decomposition of charge transfer complexes. The morphological structure were discussed and examined via Scanning Electron Microscopy (SEM).The molecular structures of Pentaprazole, DDQ, CHLC and I2& charge transfer complexes in the ground state were made by using Gaussian 03 program package.
Keyword: thermal kinetic studies, pharmaceutical drugs, benzoquinone derivatives, Computational chemistry.