African Journal of Medical Case Reports

ISSN 2756-3316

African Journal of Medical Case Reports Vol. 8 (2), pp. 001-005, February, 2020. © International Scholars Journals

Review

Potential clinical applications of dental stem cells

Veleska-Stevkovska Daniela1*, Peeva-Petreska Marija1, Evrosimovska Biljana1, Apostolova Gordana1 and Veleski Dragoljub2

1Department for Oral Surgery and Implantology, Faculty of stomatology, ”Sts Cyril and Methodius” University – Skopje, Republic of Macedonia.

2Department for Prosthodontics, Faculty of Stomatology, ”Sts Cyril and Methodius” University – Skopje, Republic of Macedonia.

Accepted 26 September, 2019

Abstract

Complex human tissues harbor stem cells and/or precursor cells, which are responsible for tissue development or regeneration. Recently, dental tissues such as periodontal ligament (PDL), dental papilla or dental follicle have been identified as easily accessible sources of undifferentiated cells. Dental precursor cells are attractive for usage in regenerative dentistry, like for example regeneration of the dental pulp (biopulp), gingiva and periodontium, regeneration of osseous defects and complete reconstruction of the temporomandibular joint. Dental stem cells are widely used in the regenerative medicine, also. Diabetes, diseases of the bone, cartilage, fibrous tissue, muscular and adipose tissue, the neurological diseases and the spinal cord injures are all included in the future cell-based therapies with dental stem cells.

Key words: Stem cells, dental pulp, cultivation, tissue engineering, clinical applications.