ISSN 2736-1756
Advanced Journal of Microbiology Research ISSN 2736-1756 Vol. 14 (6), pp. 001-007, June, 2020. © International Scholars Journals
Full Length Research Paper
Antimelanogenic and antioxidant activities of Bifidobacterium infantis
Huey-Chun Huang1, Shao-Hua Chiu2, Hui-Ju Ke2, Shu-wen Chiu2, Sze-Yun Wu2 and Tsong-Min Chang2*
1Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan, Republic of China.
2Department of Applied Cosmetology and Graduate Institute of Cosmetic Science, Hung Kuang University, Taichung, Taiwan, Republic of China.
Accepted 15 April, 2020
Abstract
The study was aimed at investigating the antimelanogenic and antioxidative effects of Bifidobacterium infantis culture filtrate. The efficacy of the bacterial culture filtrate was evaluated spectrophotometrically. The results revealed that B. infantis culture filtrate effectively scavenge 2,2-diphenyl-1-picryl-hydrazyl (DPPH) and 2,2’-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) ABTS radicals, and show potent reducing power in a dose-dependent pattern. Additionally, the bacterial culture filtrate suppresses murine B16F10 tyrosinase activity and the amount of melanin in a dose-dependent manner. We conclude that the B. infantis culture filtrate may be applied in the formulations of skin care cosmetics.
Key words: Bifidobacterium infantis, tyrosinase, melanin, antioxidant.