Global Journal of Cardiology Vol. 7 (8), pp. 001-004, August 2022. © International Scholars Journals

Full Length Research Paper

Antibacterial activity and phytochemical analysis of leaf extracts of Lasienthera africanum

Adegoke, Anthony A.1 and Adebayo-tayo, Bukola C.2

1Department of Microbiology, University of Uyo, Uyo, Akwa Ibom State, Nigeria.

2Department of Botany and Microbiology, University of Ibadan, Ibadan, Oyo State, Nigeria.

Accepted 15 May, 2022

Abstract

The phytochemical analysis of both the aqueous and methanolic extracts of edible indigenous medicinal plant Lasienthera africanum (“Editan”) and their antibacterial activities against clinical isolates, Escherichia coli, Salmonella typhi, Klebsiella pneumoniae and Staphylococcus aureus were investigated. The phytochemical analysis revealed the presence of alkaloids, saponins, tannins, flavonoids, cardiac glycosides, anthraquinones and cyanogenetic glycosides in varying concentration. Both the methanolic and aqueous extracts inhibited the growth of the test organisms with Sal. typhi showing the highest susceptibility. This research supports the local use of the leaf of the plant, L. africanum (“Editan”) for prophylactic and therapeutic purposes against bacterial infection.

Key words: Lasienthera africanum, phytochemical analysis, antimicrobial activity, activity index, therapeutic purpose.