ISSN 2756-3812
International Journal of Medical Advances and Discovery ISSN 2756-3812 Vol. 2 (6), pp. 001-004, June, 2011. © International Scholars Journals
Full Length Research paper
Mean Platelet Volume (MPV) in Intensive Care Unit (ICU) Patients: Is it a useful parameter in assessing prediction for mortality?
Yasar Kucukardali*, Yalcin Onem*, Hakan Terekeci*, Fatih Tangi*, Burak Sahan*, Alev Akyol Erikci**, Ozkan Sayan**, Selim Nalbant*, Cagatay Oktenli*
*Department of Internal Medicine, GATA Haydarpasa Training Hospital, Istanbul-Turkey
**Department of Haemotology, GATA Haydarpasa Training Hospital, Istanbul-Turkey
Accepted 20 March, 2011
Abstract
The aim of the study is to investigate MPV (mean platelet volume) showing platelet reactivity if it is associated with the severity of the critical illness or mortality in ICU patients. Study group (130 patients) was formed from survivor group (68 patients) and non-survivor group (62 patients). Platelet counts and MPV values were compared between two groups in the first five days of hospitalization. MPV correlation was studied with APACHE II score, age, haemoglobin level, duration in the ICU and as an independent risk factor in mortality. Mean age and APACHE scores were significantly higher in non-survivor group compared to survivor group (p<0.05). There was no significant difference between two groups according to MPV and platelet counts in first five days of hospitalization. There was a unique positive correlation between MPV and APACHE score (r: 0.34, p< 0.05). Only age was independent risk factor in mortality. In our study, we found positive correlation between severity of critical illness and MPV. However, there was no relation between MPV and mortality in heterogenic critical patients. Subgroup analysis of patients in ICU might be useful in assessing prediction for mortality.
Key words: Mean platelet volume, critical illness, mortality, APACHE, ICU.