ISSN 2756-3391
African Journal of Parasitology Research ISSN 2756-3391 Vol. 7 (11), pp. 001-003, November, 2020. © International Scholars Journals
Short Communication
Antimicrobial activities of ethanol extract of black grape
Abtahi H.1, Ghazavi A.2* and Karimi M.1
1Research Center of Molecular and Medicine Arak University of Medical Sciences, Arak, Iran.
2Tuberculosis and Pediatric Infectious Research Center (TPIRC), Department of Immunology, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
Accepted 09 September, 2020
Abstract
There is considerable interest in alternative/adjuvant approaches for the eradication of infections using biologically active compounds, especially antioxidants from plants. Phenolic compounds in grape products play important roles for antioxidant, anti-inflammatory, and antimicrobial effects. Grapes are rich sources of potentially bioactive polyphenols. This study was conducted to measure the antibacterial activity of ethanol extract of total grape (Vitis vinifera L., Vitaceae) against several pathogenic bacteria. Grape was extracted by percolation method. Aliquots of the extracts at variable concentrations were then incubated with different bacterial strains, and the antimicrobial activities of the ethanolic extracts from total grapes were determined by the minimum inhibitory concentration (MIC). Total grapes extract inhibited significantly, the growth of the tested bacterial strains. Among the bacterial strains tested, Staphylococcus aureus was the most susceptibleility. Results from these findings suggest that total grapes extract may be used as natural antibacterial for treatment of some diseases, especially local skin diseases.
Key words: Antimicrobial activity, grape, minimum inhibitory concentrations (MIC).