African Journal of Internal Medicine

ISSN 2326-7283

African Journal of Internal Medicine ISSN 2326-7283 Vol. 3 (10), pp. 266-275, November, 2015. © International Scholars Journals

Full Length Research Paper

Synthesis of series of macro compounds via alkylation and azotation reactions

*Hisham G. Hadid, Saddam C. Zainab and Ahmed Munir Adnan

Chemistry Department, Faculty of Medicine, University of Babylon, Hillah, Iraq.

*Corresponding author. E-mail: [email protected]

Accepted 15 October, 2015

Abstract

This paper involved synthesis of series from macro compounds through reaction between di carbonyl compounds like (cyclo hexane-1,3-dione., 1,3-diphenyl–propadione, acetyl acetone, maleic anhydride, maleic acid, malonic acid) with di amine compounds or thiophene compound to produce compounds [1-5 ,7, 8,11], which reacted with azo compound, benzaldehyde, via alkylation reaction and azotation reaction to yield compounds [6,9,10,12] .The structure of these compounds were characterized by (H.NMR, FT.IR, C.H.N–analysis) techniques and their melting points.

Key words: Macro compound, azotation, seven–membered, thiophene, diazepine, hydrazo.