African Journal of Medicine and Surgery

African Journal of Medicine and Surgery ISSN 3156-8734 Vol. 3 (3), pp. 069-073, March, 2016.  © International Scholars Journals

Full Length Research Paper

Use of MRI to monitor the location of gadolinium injections in normal humans

Justin Dion Lavigne¹*, Rachel Candy², Michael Michael³ and Norma Oscar⁴

¹Automatic Subdermal Injection System, Inc, Westminster, California, Department of Otolaryngology/Head and Neck Surgery,

²Innovative Drug Injection Technology Inc., Newport Beach, California, Department of Anesthesiology, ³Magnolia Medical Imaging Centers, Westminster/Laguna Hills/Orange, California, Department of Radiology,

⁴University of California, Los Angeles, California, Department of Otolaryngology/Head and Neck Surgery

E-mail: [email protected]

Accepted 7 February, 2016

Abstract

Our previous study which monitored human muscular contractions with an accelerometer found out that the human muscles ran away from the electrical stimuli of an electromagnetic (EMG) needle. Thus, where the needle tip must likely end up every time is just outside of the fascia, or right in the subdermal bloodless space. The current study further explored the above hypothesis by using MRI to monitor the location of gadolinium injections. Using the initial prototype of the ASIS (Automatic Subdermal Injection System) device, gadolinium was successfully injected into the subdermal bloodless space in three out of three normal subjects’ glabellas. This innovation may have a major impact on the healthcare industry because bloodless injections imply longer-lasting medication, which will benefit most, if not all, injectable products.

Key words: Subdermal bloodless space, subdermal injection, injectable EMG needle, electrical stimulation, MRI with gadolinium, muscular contractions.