ISSN 2169-303X
International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 12 (4), pp. 001-010, April, 2023. © International Scholars Journals
Full Length Research Paper
Phytonutrients content and biological activities of fruits of Diospyros mespiliformis Hoschst ex A.DC (Ebenaceae) used in the treatment of gastroenteritis and gastroduodenal ulcer in Burkina Faso
Ramde-Tiendrebeogo Alphonsine1, 4*, Bado David2, Yoda Jules1, Compaore Moussa2, Kini Felix1, Kiendrebeogo Martin2, Guissou I. Pierre3 and Guisse Aliou4
1Department of Traditional Medicine and Pharmacopoeia-Pharmacy, Research Institute in Health Sciences, National Center for Scientific and Technological Research (MEPHATRA-PH, IRSS), (CNRST), 03 BP 7047 Ouagadougou 03, Burkina Faso.
2Laboratory of Applied Biochemistry and Chemistry, Joseph KI-ZERBO University, 03 BP 7021 Ouagadougou 03, Burkina Faso.
3St Thomas d’Aquin University, Faculty of Health Sciences (USTA), 06 BP 10212 Ouagadougou 06 Burkina Faso.
4International Research Laboratory IRL 3189 Environment, Health, Societies (CNRST, USTTB, UCAD, UGB, CNRS).
Accepted 14 April, 2023
Abstract
Digestive disorders occupy the second place of the major health problems in Burkina Faso. The fruits of Diospyros mespiliformis are used in recipes to treat gastroenteritis and gastroduodenal ulcer. Phytonutrients content was evaluated by specific reagents and biological activities by antiradical and antibacterial test. The fruit seed of Diospyros mespiliformis had the best antioxidant activity (IC50 = 0.04 mg/mL) due to its content of total phenolic compounds (5.75 ± 0.6 mg GAE/g), flavonoids (0.78 ± 0.27 mg RE/g), hydrolyzable and condensed tannins (3.56 ± 0.03 mg TAE/g; 1.28 ± 0.42 mg CE/g) compared to the pulp whose content were 3.36 ± 0.12 mg GAE/g ; 0.46 ± 0.26 mg RE/g; 1.78 ± 0.35 mg TAE/g and 0.56 ± 0.11 mg CE/g respectively for total phenolic, flavonoids, hydrolysable and condensed tannins. The fruit seed had the best content of macronutrients (Na, K, Mg) and showed important antibacterial activity against E. coli. The fruit pulp had the best content of vitamin C, b-carotene and vitamin E, being 22.0 ± 0.01mg/100g; 0.007 ± 0.03 mg/100g and 0.119 ± 0.02 mg/100g respectively. The results constitute scientific prerequisites for the development of new functional foods and phytomedicines in the management of digestive disorders.
Key words: Digestive diseases, medicinal plant, radical scavenging, mineral elements, nutraceutical.