International Journal of Medicinal Plants Research

International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 6 (4), pp. 332-336, April, 2017. © International Scholars Journals

Full Length Research Paper

Antiulcerogenic effect of extracts of Momordica Balsamina Linn against experimentally induced gastric ulceration in rats

SH Mshelia and Y Karumi

Department of Biochemistry, University of Maiduguri, Maiduguri, Borno State, Nigeria.

*Corresponding author E-mail: [email protected]

Accepted 16 November, 2013

Abstract

Various doses of extracts of Momordica Balsamina was administered to wistar rats to test for antiulcerogenic activity in ulcer induced gastric ulceration. The various doses of extracts administered were 100mg/kg, 200mg/kg, 400mg/kg and 800mg/kg. These doses displayed ulcer inhibition rates ranging from 34.40% - 70.70% as compared to that of ranitidine which showed an ulcer inhibition rate of 72.66 %. This result therefore shows that Momordica Balsamina has potential to serve as an antiulcerogenic agent therefore offering another ethnobotanical use for this all-important medicinal plant.