ISSN 2375-1258
African Journal of Dairy Farming and Milk Production ISSN 2375-1258 Vol. 8 (3), pp. 001-005, March, 2020. © International Scholars Journals
Full Length Research Paper
Protective efficacy of commercial live vaccines against very virulent infectious Bursal disease virus (vvIBDV) in Ghana
H. R. Otsyina1*, J. Amakye-Anim2 and K. G. Aning1
1Animal Research Institute, CSIR, P. O. BOX AH 20. Achimota, Accra – Ghana.
2La Veterinary Hospital, P. O. Box C2402. Cantoments, Accra, Ghana.
Accepted 09 September, 2019
Abstract
In spite of the intensive and varied vaccination procedures to control Infectious Bursa Disease (IBD), the emergence of a very virulent (vv) IBD pathotype in Ghana has led to high economic losses in the poultry industry. The potencies of two live intermediate IBD vaccine strains (TAD and Nobilis D78) and an intermediate-plus (hot) vaccine strain (228E) used in Ghana were evaluated by challenging Specific Antibody Negative (SAN) chicks with a vvIBD virus (LV/G19) which was recently isolated in Ghana. Serum samples were obtained from all chicks before vaccination and virus challenge. Antibody titres were measured by Enzyme-linked Immunosorbent assay (ELISA). Body weight, bursal weight and bursa to body weight measurements were also taken. All vaccinated chicks were fully protected from the vvIBD virus, as neither morbidity nor mortality was observed in the vaccinated chicks after challenge. The intermediate–plus (hot) IBD vaccine elicited the highest antibody titers but caused reduction in the size of the bursa of Fabricius. Taken together, the results of this study showed that vaccines currently in use in Ghana can protect chicken against the locally-isolated vvIBD virus.
Key words: Infectious bursal disease, vaccine efficacy, intermediate, intermediate-plus (hot).