ISSN 2169-303X
International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 7 (9), pp. 410-413, September, 2018. © International Scholars Journals
Full Length Research Paper
A study of the relative free radical scavenging activity in selected Iranian medicinal plant species
F. Pourmorad1*, S. J. Hosseinimehr1, N. Shahabimajd2
1Department of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
2Department of Physiology and Pharmacology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
*Corresponding author. E-mail: [email protected]. Tel: 0098 911 152 2396 (mobile). Fax: 0098 152 3343082.
Accepted 25 September, 2017
Abstract
In present study, we carried out a systematic record of the relative antioxidant activity in selected Iranian medicinal plant species' extracts. The total phenol varied from 24.1 ± 1 to 289.5 ± 5 mg g -1 in the extracts. Flavonoid contents were between 25.15 ± 0.8 and 78.3 ± 4.5 mg g-1. 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging effect of the extracts was determined spectrophotometrically. The highest radical scavenging effect was observed in Mellilotus officinalis with IC50 = 0.018 mg ml –1. The potency of radical scavenging effect of M. officinalis extract was about 4 times greater than synthetic antioxidant butylated hydroxy toluene (BHT). The greater amount of phenolic compounds leads to more potent radical scavenging effect as shown by M. officinalis extract.
Key words: Antioxidant, radical scavenger, flavonoids, phenols, 1,1-diphenyl-2-picryl hydrazyl.