ISSN 2756-3391
African Journal of Parasitology Research ISSN 2756-3391 Vol. 7 (11), pp. 001-006, November, 2020. © International Scholars Journals
Full Length Research Paper
Giardia intestinalis and Entamoeba histolytica: Their Prevalence and Hematological Effects on Children between Seven Months to Seven Years at the Mother and Child Teaching Hospital in N’Djamena, Chad
Fombotioh Ndifor1, Hamit Mahamat Alio*1,2, Issa Ramat Adam1,3, Abakar Idriss Lawane1,4 and Foumsou Lhangadang1.
1Department of Biomedical Sciences and pharmacy, Faculty of human health sciences, University of N’Djamena. P.O. Box: 1117, N’Djamena, Chad.
2Laboratory of Parasitology and Ecology, Faculty of Sciences, P.O. Box. 812 Yaounde, Cameroon.
3Faculty of Sciences, University of Douala, BP 24157 Douala, Cameroon.
4Laboratory of Biochemistry and Applied Immunology (LABIA), Joseph KI-ZERBO University, Burkina Faso, 03. P.O. Box 7021, Ouagadougou, Burkina Faso.
Accepted 08 November, 2020
Abstract
This study was to assess the prevalence of Giardia intestinalis and Entamoeba histolytica and their hematological effects on children between 7 months to 7 years at the mother and child teaching hospital of N’Djamena. Patients consisted of 200 children who were brought for consultation in the paediatric ward. Our work started from November 2019 to April 2020. Stool samples were collected from patients and examined by direct smears and Willis floatation technique. Hematological parameters examined were: hematocrit, Hemoglobin, red blood cells, leucocytes and eosinophils. From the population studied, 42% had gastrointestinal protozoa infections. Our study recorded the prevalence of Giardia intestinalis (25%) and Entamoeba histolytica (75%). Parasites were isolated from all the age groups. Infections were higher in males 25% than in females 16.66%. Patients infected presented lower average of hematocrit 30%, hemoglobin 8.62±1.043, red blood cells 2.64±0.38, leucocytes 13.73± 2.62 and eosinophils 6.16%. The most frequent symptoms observed for both parasites were diarrhoea 25 (12.5%), abdominal pain 25 (12.5%), abdominal pain and diarrhoea 21(10.5%) and digestive discomfort 13(6.5%). This study noticed a strong prevalence of E. Histolytica and G.intestinalis among the children. A statistical significant different was found between infected and the non-infected subjects (P ˂ 0.05).
Key words: Giardia intestinalis, Entamoeba histolytica, prevalence, Hematological, child, Chad.