ISSN 4391-3199
African Journal of Chemistry ISSN 4391-3199 Vol. 5 (5), pp. 329-334, May, 2018. © International Scholars Journals
Full Length Research Paper
Oxovanadium (IV) esters of ciprofloxacin: Their characterization and potentiometric study
Saira Shahzadi1* and Saqib Ali2
1Department of Chemistry, GC University, Faisalabad, Pakistan.
2Department of Chemistry, Quaid-i-Azam University, 45320 Islamabad, Pakistan.
Accepted 07 October, 2017
Abstract
The reaction between ciprofloxacin and VOSO4.3H2O in 1:1, 1:2 and 1:3 molar ratio in methanol was investigated at 20˚C, 0˚C and -10˚C. In various pH conditions the different complexes which are formulated as VO(H2O)3L, VO(H2O)L2 and VL3 have been formed by titration of VOSO4.3H2O with ciprofloxacin in the presence of NaOH. These complexes have been characterized by IR spectroscopy. The order of stability is estimated as 1:1 >1:3 >1:2 which is justified by the proposed mechanism.
Key words: Oxovanadium (IV) esters, IR, potentiometric study, stability constant.