ISSN 2329-9835
International Journal of Diseases and Disorders ISSN 2329-9835 Vol. 7 (5), pp. 001-004, May, 2019. © International Scholars Journals
Full Length Research Paper
Screening of cytomegalovirus seroprevalence among pregnant women in Ankara, Turkey: A controversy in prenatal care
Ayla Sargin Oruç1*, Şevki Çelen1, Ayşe Çitil1, Sibel Saygan2, Serpil Ünlü3 and Nuri Danişman1
1Obstetrics and Gynecology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, 06230, Turkey.
2Microbiology and Clinical Microbiology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, 06230, Turkey.
3Infectious Disease and Clinical Microbiology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara 06230, Turkey.
Accepted 11 November, 2018
Abstract
Cytomegalovirus (CMV) seropositivity is common among pregnant women. CMV is the most common of the teratogenic viruses and is a leading cause of neurological impairment in newborns, especially sensorineural deafness. The aim of this study was to determine the seroprevalence of CMV among pregnant women in a tertiary maternity hospital setting in Ankara, Turkey. The study was conducted on 11,360 pregnant women in the first trimester admitted to Zekai Tahir Burak Women’s Health Education and Research Hospital in Ankara, Turkey, between the years 2008 to 2010. Of the 11360 women, 11189 (98.5%) and 35 (0.3%) were seropositive for ImmunoglobulinG (IgG) and ImmunoglobulinM (IgM) anti-CMV antibodies, respectively. Evaluations of age-specific subgroups indicated high CMV seropositivity rates for all age groups. CMV seropositivity is common among pregnant women. Widespread population screening may aid in preventing congenital infections by this agent. Seroprevalence studies are needed to assess the burden of infection, to identify groups at special risk and to aid in the design of future preventive measures and vaccine strategies.
Key words: Cytomegalovirus (CMV), seroprevelance, pregnancy, avidity.