African Journal of Internal Medicine

ISSN 2326-7283

African Journal of Internal Medicine ISSN 2326-7283 Vol. 8 (2), pp. 001-002, February, 2020. © International Scholars Journals

Case Report

Microscopic thymoma accompanying simple thymic hyperplasia

Elif U. Akyildiz1*, Hale Demir2, Ahmet Demirkaya3, Canan Akman4, Buge Oz1 and Nil U. Comunoglu5

1Department of Pathology, Uludag University School of Medicine, Gorukle, Bursa, Turkey.

2Departments of Pathology, Cerrahpa a School of Medicine, Istanbul University, Istanbul , Turkey.

3Thoracal Surgery, Cerrahpa a School of Medicine, Istanbul University, Istanbul, Turkey.

4Radiology, Cerrahpa a School of Medicine, Istanbul University, Istanbul, Turkey.

5Department of Pathology, Yeditepe University School of Medicine, Kayısda ı, Istanbul, Turkey.

Accepted 11 May, 2019

Abstract

Thymic pathologies such as lymphoid follicular hyperplasia or thymoma are seen in 75% of myasthenia gravis subjects. Microscopic thymoma is a lesion that is seen in 15% of myasthenia gravis patients. The World Health Organization defines microscopic thymoma as a “ usually multifocal epithelial proliferation <1 mm in diameter”. Microthymoma, in other words microscopic-sized thymoma, should be considered in the differential diagnosis of microscopic timoma. We present the case of a 28-year-old male patient followed-up for myasthenia gravis and diagnosed with “microscopic thymoma” following thymectomy.

Key words: Thymus, microscopic thymoma, thymoma, myasthenia gravis.