ISSN 2756-3391
African Journal of Parasitology Research ISSN 2756-3391 Vol. 12 (8), pp. 001-003, August, 2024. Available online at www.internationalscholarsjournals.org © International Scholars Journals
Short Communication
Antimicrobial Properties of Chloroform Extracts from the Roots and Stems of Andrographis paniculata Nees
Parvataneni Radhika1* and Koduru Rajya Lakshmi2
1Department of Biochemistry, Andhra University, Visakhapatnam 530 003, Andhra Pradesh, INDIA
2Pharmaceutical and Medicinal Chemistry Division, University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam 530 003, Andhra Pradesh, INDIA
Accepted 20 May, 2024
Abstract
In vitro antibacterial and antifungal activity of the chloroform extracts of the root and the stem of Andrographis paniculata at different concentrations were screened against gram positive bacteria Staphylococcus aureus, Bacillus subtilis, gram negative bacteria Escherichia coli, Proteus vulgaris and fungi Aspergillus niger, Penicillium chrysogenum by cup plate method. The extracts were found to inhibit the growth of all the bacteria and fungal organisms tested. The effect produced by the extracts were comparable with the standard antibacterial agent, benzyl penicillin and with the standard antifungal agent, fluconazole and were found to be active against all the organisms tested.
Keywords: Andrographis paniculata, stem, root, chloroform extracts, antibacterial activity, antifungal activity.