ISSN 2736-1594
International Journal of Obstetrics and Gynecology ISSN: 2326-7234 Vol. 3 (3) pp. 072-076, May, 2015. © International Scholars Journals
Full Length Research Paper
Exploratory endometriosis reduction in rats treated with pioglitazone
*Zhuo Zetian, Jiang S. Kar-wai and Guan V. Salim
Department of Obstetrics and Gynecology, University of Hong Kong, Hong Kong, China.
E-mail: [email protected]
Accepted 7 April, 2015
Abstract
The objective of this paper was to assess the effectiveness of the pioglitazone on endometriosis in rats. The study was performed on 24 Wistar rats. Endometriosis induction was performed in 24 rats, which were divided into three groups: group I (model group); and group II, the treatment group, comprising the other 12 rats. After 3 months, pioglitazone was performed in all animals. Pioglitazone treatment seems to be effective in treatment of endometriosis.
Key words: Pioglitazone, endometriosis, uterine implant, NF-kB p65, IkBα.