ISSN 2326-7275
International Journal of Anatomy and Physiology ISSN: 2326-7275 Vol. 7 (4), pp. 001-004, April, 2018. © International Scholars Journals
Full Length Research Paper
Volatile constituents and anti candida activity of the aerial parts essential oil of Dittrichia graveolens (L.) Greuter grown in Iran
Nasrin Aghel1*, Ali Zarei Mahmoudabadi2 and Loobat Darvishi1
1Medicinal Plant Research Center, Department of Pharmacognosy, School of Pharmacy, Jundishapour Medical Sciences University, Ahwaz, Iran.
2Infectious and Tropical Diseases Research Center, Department of Medical Mycology, School of Medicine, Jundishapour Medical Sciences University, Ahwaz, Iran.
Accepted 30 May, 2017
Abstract
The aims of present study were to analysis of chemical compositions and evaluate anti-Candida activity of Dittrichia gravolence essential oil. The composition of the hydrodistilled essential oil from aerial parts of D. graveolens (L.) Greuter were grown in Iran investigated by gas chromatography-mass spectroscopy (GC/ MS). The major components, among the identified 22, were 1,8 Cineol (54.89%), P-Cymen (16.2%), [beta]-pinene (6.94%) and Borneol (5.44%) . Anti-Candida activity of the volatile oil of the aerial parts of D. gravolence against different isolates of Candida albicans was studied in vitro. Anti-Candida activity was done using serial dilutions of volatile oil in Sabouraud’s dextrose agar (SDA). Agar well diffusion methods was used for detection minimum inhibitory concentration (MIC). MIC for 10 isolates of tested yeasts was 30.675 mg/ml.
Key words: Dittrichia graveolens, essential oil, 1,8 Cineol, Candida albicans.