ISSN 2326-7275
International Journal of Anatomy and Physiology ISSN: 2326-7275 Vol. 5 (12), pp. 001-005, December, 2016. © International Scholars Journals
Full Length Research Paper
Polysaccharides from Portulaca oleracea (purslane) supplementation lowers acute exercise induced oxidative stress in young rats
Lou Xiaojuan1*, Huang Yong2, Guo Xueqi1, Zheng Fanhui3, Jiang Zhihong4 and Yang Yong ping1
1Donghua University, Shanghai 201620, PR, China.
2Tongji University, Shanghai 200092, PR. China.
3Shanghai Research Institute of Sports Science, Shanghai 200030, PR, China.
4Zhejiang Sci-Tech University, Hangzhou 310018, PR, China.
Accepted 21 March, 2016
Abstract
The present study was designed to determine the effects of polysaccharides from purslane (PFP) supplementation on acute exercise induced oxidative stress in young male Sprague-Dawley rats. Animals were divided randomly into four groups, that is control group (C), low-dose PFP supplemented group (LP), middle-dose PFP supplemented group (MP) and high-dose PFP supplemented group (HP). Each group contains eight animals. The mice in the control group were orally administered physiological saline of 50 ml/kg bodyweight per day for 30 days, while the PFP supplemented group received the same volume of PFP of 100, 200 and 400 mg/kg bodyweight. On the final day of the study, rats were exercised to exhaustion (22 m/min at 10% inclination on the treadmill) and then all the rats were sacrificed. Body weight, running time, blood lactate, malondialdehyde (MDA), superoxide dismutase (SOD), and glutathione peroxidase (GPX) of rats were measured. Results of the above study showed that PFP supplementation could elevate the exercise tolerance and inhibited the production of blood lactate during acute exercise. PFP supplementation lowers exercise induced oxidative stress by means of decreasing SOD, GPX activities and MDA level in skeletal muscle of young rats.
Key words: Polysaccharides from purslane, acute exercise, oxidative stress, rats.