ISSN 2167-0404
International Journal of Medicine and Medical Sciences Vol. 1(1), pp. 017-019, 27 November, 2011, ISSN: 2167-0404 © International Scholars Journals
Full Length Research Paper
Chlamydia Infection and Infertility: Any Relationship? The Lagos State University Teaching Hospital Experience
Tayo AO*, Akinola OI*, Ottun TA*, Babatunde A*, Shakunle B**
1Department of Obstetrics and Gynaecology, Lagos State University Teaching Hospital, Ikeja, Lagos.** Chief Medical Laboratory Scientist,
2Department of Obstetrics and Gynaecology, Lagos State University College of Medicine, (LASUCOM) Ikeja, Lagos.
*Corresponding Author's E-mail: [email protected]
Received 27 October 2011; Accepted 27, November, 2011
Abstract
Chlamdyia trachomatis having been recognized as a sexually transmitted pathogen has also been associated with infertility. 50 women with infertility (both primary and secondary) and 50 women matched for age attending the Postnatal Clinic were studied. Endocervical swabs and venous blood were collected from each of the subjects. Both samples were subjected to laboratory investigations for Chlamydia trachomatis IgG and IgM antibodies. Result: All patients were negative on Endocervical swab for Chlamydia; however 32.1% of the infertile had positive chlamydia assay whilst 21.3% of the control had. It was also found out that patients with positive Chlamydia assay are 1.747 times at risk of infertility compared with patients with negative assay. Prior Chlamdia trachomatis infection constitutes a risk factor for infertility in this environment.
Keywords: Chlamydia trachomatis, Infertility, Infection, Antibodies, Endocervical swabs, Pelvic Inflammatory Disease, Positive Chlamydia Assay