ISSN 2756-3820
International Journal of Medical Sociology and Anthropology ISSN 2756-3820 Vol. 15 (2), pp. 001-005, February, 2026. Available online at www.internationalscholarsjournals.org © International Scholars Journals
Full Length Research Paper
Antisecretory and Antimotility Effects of Azima tetracantha Leaf Extract in Experimental Diarrhoea
V. Hazeena Begum*, M. Dhanalakshmi and P. Muthukumaran
Department of Siddha Medicine, Faculty of Science, Tamil University, Vakaiyur, Thanjavur 613 010, Tamilnadu, India.
Accepted 3 October, 2025
The aqueous crude extract of the leaves of Azima tetracantha was studied for its phytochemical constituents and antidiarrhoeal activity using castor oil-induced diarrhoea and castor oil-induced enteropooling in rats. The phytochemical studies of the aqueous extract revealed the presence of alkaloids, flavonoids, tannins and saponins. The extract showed significant (p < 0.001) protection against castor oil-induced diarrhoea and castor oil-induced enteropooling at (100 mg/kg). The presence of some of the phytochemicals in the root extract may be responsible for the observed effects, and also the basis for its use in traditional medicine as antidiarrhoeal drug.
Key words: Azima tetracantha, enteropooling, anti-diarrhoeal.