ISSN 2169-303X
International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 8 (1), pp. 001-009, January, 2019. © International Scholars Journals
Full Length Research Paper
Phytochemical and biological investigation of Tanacetum parthenium (L.) cultivated in Egypt
Mostafa E. M. Rateb1, Abdel-Nasser A. M. El-Gendy2, Seham S. El-Hawary3 and Ali M. El-Shamy3
1Pharmacognosy Department, Faculty of Pharmacy, Beni-Sueif University, Egypt.
2Pharmacology Department, Faculty of Veterinary Medicine, Beni-Sueif University, Egypt.
3Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Egypt.
Accepted 17 October, 2018
Abstract
Phytochemical investigation of Tanacetum parthenium (L.) family Asteraceae cultivated in Egypt resul-ted in isolation and identification of four flavonoids isolated from the aerial part, four sesquiterpene lactones isolated from the leaves, two sterols isolated from the roots. A comparative study of the essential oil content of the leaves and the flower heads was performed using (GC/MS) revealing the presence of 42 and 30 components with the major components camphor (constituted 37.7 and 48.4%) and chrysanthenyl acetate (constituted 33.8 and 26.3%) in the leaves and the flower heads, respectively. Different extracts of T. parthenium (L.) showed significant analgesic, anti-inflammatory, antipyretic, antispasmodic and uterine-stimulant activities in addition to the in vitro cytotoxic effect.
Key words: Tanacetum parthenium, ethanol and water extracts, essential oil, analgesic, anti-inflammatory, antipyretic, antispasmodic, uterine stimulant and cytotoxic.