ISSN 2756-3855
International Journal of Urology and Nephrology ISSN 2091-1254 Vol. 7 (8), pp. 001-011, August, 2019. © International Scholars Journals
Full Length Research Paper
Impact of fungal content of some Arabic nuts to induce kidney toxicity and agonistic action of natural resources
A. A. Saddiq and S. A. Kalifa*
Department of Biology, Faculty of Science, King Abdul-Aziz University, Jeddah, Kingdom of Saudi Arabia.
Accepted 18 February, 2019
Abstract
Human and animals are exposed to a great extent of the danger of mycotoxic infection and their toxins due to wide spread of fungal growth on grains and food. Aflatoxin B1 (AFB1) is one of the most dangerous toxins that are produced by fungi as a secondary metabolic products. This study aims to isolate and identify the fungi from some grains present in Arabian nuts. 30 samples were collected from commercial stores in Jeddah in the period from 2008 to 2009. Histological study was done on female rat kidney that was treated with isolated fungus Aspergillus flavus and the carcinogenic substance aflatoxin B1 (AFB1). Results showed the occurrence of several harmful effects of the experimental fungi and AFB1 on the kidney. Effects of “musk” and “sidr” extract as natural treating sources were confined in this study. They proved their effectiveness in treating renal mycotoxicity.
Key words: Arabian nuts, Aspergillus flavus, aflatoxin B1, kidney, musk deer, sidr.