ISSN 2756-3391
African Journal of Parasitology Research ISSN 2756-3391 Vol. 12 (9), pp. 001-007, September, 2024. Available online at www.internationalscholarsjournals.org © International Scholars Journals
Full Length Research Paper
Genotyping of HLA-DQA1 and HLA-DQB1 in Patients with Gastritis and Positive Rapid Urease Test Results
Nibras S. Al-Ammar1, Ihsan E. Al-Saimary1, Saad Sh. Hamadi2, Ma Luo2, Trevor Peterson1 and Chris Czarnecki2
1Department of Microbiology, College of Medicine, University of Basrah, Basrah, Iraq
2Department of Medicine, College of Medicine, University of Basrah, Basrah, Iraq
Accepted 26 July, 2024
Abstract
To study was carried out to know HLA-DQA1 and HLA-DQB1 genotyping in gastritis patients with positive and negative RUT. This study was carried out in College of Medicine, University of Basrah. HLA-DQA1 and HLA-DQB1 genotyping was done in College of Medicine, University of Manitoba, Winnpeg, Canada during the period from April 2009 to July 2010. A total of 70 gastritis patients, 29 males and 41 females, were included in this study. Significant increased frequencies of DQB1*050101 and DQB1*050201 alleles were found in gastritis patients who showed (+ RUT), but with weak association (odds ratios were 0.83 and 0.79 respectively), as compared with gastritis patients who showed (- RUT).
Keywords: Genotype, HLA-DQA1 & HLA-DQB1, Gastritis, Iraq.