ISSN 4391-3199
African Journal of Chemistry ISSN: 4391-3199 Vol. 3 (1), pp. 132-141, January, 2016. © International Scholars Journals
Full Length Research Paper
Electrochemical studies of Tram and DA in real pharmaceutical and human serum samples
Nefertiti Morsi1*, Mohammed Rufi2, Ibrahim O. Mubarak1 and Hassan V. Hamama1
1Electrochemistry Laboratory, Chemistry Department, Egyptian Petroleum Research Institute, Nasr City, Cairo, Egypt.
2Faculty of Science, Ain Shams University, Cairo, Egypt.
E-mail: [email protected]
Accepted 7 December, 2015
Abstract
Modified platinum electrode based on the poly 8-(3-acetylimino-6-methyl-2,4-dioxopyran)-1-aminonaphthalene (PAMDAN) film was prepared by electrochemical polymerization technique. The modified electrode showed electrocatalytic activity toward tramadol (Tram) oxidation in acidic aqueous solution. It was demonstrated that Pt electrode modified by PAMDAN film (PAMDAN/Pt modified electrode) could be used for Tram detection using cyclic voltammetry (CV) and square wave voltammetry (SWV) techniques. This modified electrode was quite effective not only for detecting Tram, but also for simultaneous determination of Tram and dopamine (DA) in a mixture with satisfactory results.
Key words: Voltammetry, electrocatalysis, electro analysis, tramadol, dopamine, simultaneous determination.