ISSN 2169-303X
International Journal of Medicinal Plants Research ISSN 2169-303X Vol. 13 (3), pp. 001-005, March, 2024. Available online at www.internationalscholarsjournals.org © International Scholars Journals
Full Length Research Paper
Boosting vaccine effectiveness: An investigation into the impact of Chinese medicinal herbs and their immune synergists on classical swine fever vaccination
Fuchuan Wang1, Yibo Yan1*, Yuhuan Zhang1, Yichao Han1 and Chao Guan2
1Institute of Animal Husbandry and Veterinary Sciences, Shanxi Academy of Agricultural Sciences, Taiyuan 030032, China.
2Modern Agricultural Research Center, Taiyuan 030000, China.
Accepted 22 October, 2023
Abstract
Two-month-old piglets were fed with 1, 1.5 and 2% immune synergist of Chinese medicinal herbs together with vaccination against classic swine fever. Serum IgG and IgM levels increased more than the control group on day 30 (P<0.05). B and T lymphocyte proliferation in piglets fed with 1.5 and 2% herbal immune synergist markedly increased on day 30 as compared to the control group (P<0.05). Improvement was also observed in T lymphocyte CD3+, CD4+, CD8+ and CD3+/CD8+ levels. Meanwhile, there were significant differences in SOD activities and rate of neutrophil phagocytosis between synergist groups and the control group. These results suggest that herbal immune synergist of Chinese traditional herbs prescription enhances the protective effect of classic swine fever vaccine.
Key words: Immune synergist, Chinese medicinal herbs, classic swine fever vaccine.