ISSN 2375-1134
African Journal of Agriculture ISSN 2375-1134 Vol. 7 (10), pp. 001-004, October, 2020. © International Scholars Journals
Full Length Research Paper
Biological activities of extracts from a naturally wild kiwifruit, Actinidia macrosperma
Yin Lu1,2*, Yunpeng Zhao2 and Chengxin Fu2
1College of Biological and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310015, Zhejiang Province, P. R. China.
2College of Life Science, Zhejiang University, Hangzhou, P. R. China.
Accepted 18 April, 2020
Abstract
Actinidia macrosperma C. F. Liang is a medicinal plant in China and has been well known for its attraction to cats and activities against leprosy and cancers. In this paper, the petroleum ether, chloroform, ethyl acetate, n-hexane and aqueous successive extracts from the stems of A. macrosperma were screened for antibacterial and antifungal activities in vitro for the first time, using the disc diffusion method, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) / minimum fungicidal concentration (MFC). General toxicity of these extracts has also been assessed by brine shrimp lethality assay. From the results, the chloroform extract exhibited the most significant antimicrobial (MIC in the range of 60 to 500 µg/mL, MBC in the range of 150 to 1000 µg/mL, MFC in the range of 170 to 600 µg/mL) and cytotoxic activities (LC50 = 16.82 µg/mL at 24 h).
Key words: Actinidia macrosperma; antimicrobial activity, cytotoxicity, brine shrimp.