African Journal of Internal Medicine

ISSN 2326-7283

African Journal of Internal Medicine ISSN 2326-7283 Vol. 3 (10), pp. 237-238, November, 2015. © International Scholars Journals

Short Communication

An evaluation of the efficacy of platelet rich plasma (PRP) in regeneration of bone in defects of the oral and maxillofacial region

Omar M. Ambani

Department of Pharmacology, Faculty of Medicine, University of Mumbai, India.

*Corresponding author. E-mail: [email protected].

Accepted 18 October, 2015

Abstract

The aim of this study is to evaluate the efficacy of platelet rich plasma (PRP) in regeneration of bone in defects of the oral and maxillofacial region. A comparative nonrandomized study including 40 patients with bony defects of the maxillofacial region was carried out in the Department of Oral and Maxillofacial Surgery. Patients were divided into two groups: group A received PRP and in group B no graft was used. Postoperatively, the patients were monitored regularly by radiographs to evaluate new bone growth at 1st, 3rd and 6th month clinically and radiographically. Faster bone healing was observed in the patients in whom PRP was used at every follow up. Defects filled with PRP showed comparatively earlier and faster bone regeneration.

Key words: Bony defects, platelet-rich plasma, platelets.