International Journal of Urology and Nephrology

ISSN 2756-3855

International Journal of Urology and Nephrology ISSN 2091-1254 Vol. 4 (5), pp. 128-135, November, 2016. © International Scholars Journals

Full Length Research Paper

The burden of mental-physical fatigue and its correlates in patients undergoing hemodialysis and peritoneal dialysis

Vesile SENOL1, Murat Hayri SIPAHIOGLU2, Pelin NAR SENOL3 *, Mahmut ARGUN4, Ahmet OZTURK5

1Health Services Vocational College, Erciyes University, Kayseri, Turkey.

2Department of Nephrology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.

3Department of Neurology, Faculty of Medicine, Uludag University, Bursa, Turkey.

4Department of Orthopedy and Traumatology, Faculty of Medicine, Erciyes University, Kayseri Turkey.

5Department of Biostatistics, Faculty of Medicine, Erciyes University, Kayseri.

Received 09 March, 2016; Revised 28 November, 2016; Accepted 01 December, 2016 and Published 05 December, 2016

Corresponding author E-mail: [email protected]

Abstract

Fatigue is a debilitating symptom in patients with end-stage renal disease. This study was aimed to determine the level and correlates of physical and also mental fatigue symptoms in addition to its effect on health related quality of life (HRQoL) in hemodialysis (HD) and peritoneal dialysis (PD) patients. A questionnaire-based cross-sectional study involving 318 patients was conducted in three dialysis centers. Data were collected using the Fatigue Severity Scale (FSS), Short-Form 36, Beck Depression Inventory (BDI) and Arizona Sexual Experiences Scale (ASEX). Patient groups were identified as having fatigue (FSS >4.0), depressive (BDI ≥17) and having sexual dysfunction (SD) (ASEX ≥12). Fatigue prevalence was 71.6% in HD patients and 66.9% in PD patients. Depression prevalence was 43.7% and most of the depressive patients (87.8%) had fatigue. SD prevalence was 77.8% and 75.2% of them had fatigue. MCS and PCS scores were markedly lower in fatigued patients. FSS was correlated with BDI, PCS and MCS scores in both HD and PD patients. Fatigue was similarly frequent and severe in both types of dialysis groups and this seriously impaired HRQoL. Depression and physical HRQoL were the major predictors of fatigue in both groups.

Key words: Kidney failure-chronic, renal dialysis, peritoneal dialysis, fatigue, mental fatigue, quality of life, chronic diseases and depression.