International Journal of Public Health and Epidemiology
International Journal of Public Health and Epidemiology ISSN 2326-7291 Vol. 11 (6), pp. 001-005, June, 2022. © International Scholars Journals
Full Length Research paper
Antibiotic susceptibility and plasmid pattern of Pseudomonas aeruginosa from the surgical unit of a university teaching hospital in north central Nigeria
A. T. Olayinka1*, B. O. Olayinka2 and B. A. Onile3
1Department of Medical Microbiology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
2Department of Medical Microbiology and Parasitology, University of Ilorin, Ilorin, Nigeria
3Department of Pharmaceutics and Pharmaceutical Microbiology, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria, Nigeria.
Accepted 25 February, 2022
This study determined the susceptibility pattern and multiple antibiotic resistance (MAR) index of 92 Pseudomonas aeruginosa strains from clinical samples comprising mainly urine (51.1%) and wounds (41.3%) obtained from the surgical units of Ahmadu Bello University Teaching Hospital, Zaria, Nigeria; over a 24-month period. The strains were susceptible to imipenem (94.6%), ciprofloxacin (90.2%), amikacin (89.1%) and ceftazidime (78.3%) but resistant to ofloxacin (82.6%), perfloxacin (58.7%) and gentamicin (35.8%). Analysis of the MAR index of isolates revealed that 60.9% had MAR index of 0.3 and above, which is an indication of probable origin from the hospital environment where antibiotics are extensively used. A strict management of antibiotic policies and a continuous surveillance programme for multidrug resistant pathogens like P. aeruginosa in specialised units is advocated.
Key words: Antibiotic resistance, plasmid, Pseudomonas aeruginosa
List of Other Journals
[Abstract][Full Article - PDF][Download Full Article - PDF]https://doi.org/10.46882/IJPHE/1241Search Pubmed for articles by:A. T. Olayinka* B. O. Olayinka B. A. OnileSearch Google Scholar for articles by:A. T. Olayinka* B. O. Olayinka B. A. OnilePreferencesRelated ArticlesEmail this Article to a friendPrint this ArticleArticle Access Statistics
PDF Downloaded 261