International Journal of Medical Advances and Discoveries

International Journal of Medical Advances and Discovery ISSN 2756-3812 Vol. 7 (1), pp. 001-003, January, 2020. © International Scholars Journals

Short  Communication

Primary non Hodgkin’s lymphoma of the orbit: A case report

Essadi1 I, Tazi2  EM, Allam2 W, Sbitti1 Y, Ichou1 M and Errihani2 H

1Department of Medical Oncology, Military Hospital MOHAMMED V, Rabat, Morocco.

2Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.

Accepted 09 December, 2019


Lymphoma is the most common malignancy of the orbit and the eyelids, accounting for 10% of malignant orbital tumors in adults. Orbital lymphomas can arise primarily in the orbit or represent a manifestation of disseminated disease. In this paper we report a case of early stage orbital lymphoma, which was managed successfully with chemotherapy, and a review of the related literature. A Moroccan Muslim woman aged 76 years, who presented a left orbital swelling. Ophthalmological examination complemented by CT has objectified orbital mass, whose biopsy was in favour of a non Hodgkin's lymphoma (NHL) large cell B. The patient was classified as stage IE after a record expansion. She was managed successfully with 6 courses of Rituximab 375 mg/m², Cyclophosphamide 750 mg/m² d1, Doxorubicine 50 mg/m² d1, Vincristine 1.4 mg/m² d1, and prednisone 50 mg/m² d1-5 (R-CHOP) regimen, with complete response. This case highlights the important role of R-CHOP regimen for achieving successful treatment cure for patients having an early stage orbital lymphoma

Key words: Orbit, non hodgkin’s lymphoma, large cell, chemotherapy.