African Journal of Medicine and Surgery

African Journal of Medicine and Surgery ISSN 2756-3324 Vol. 7 (10), pp. 001-005, October, 2020. © International Scholars Journals

Full Length Research Paper

Analysis of factors influencing the efficacy of percutaneous retrogasserian glycerol rhizotomy in patients with idiopathic trigeminal neuralgia

Lunshan Xu and Minhui Xu*

Department of Neurosurgery, Daping Hospital of the Third Military Medical University, Chongqing 400042, China.

Accepted 23 August, 2020

Abstract

Our study analyzed the factors influencing the efficacy of percutaneous retrogasserian glycerol rhizotomy in patients with idiopathic trigeminal neuralgia. Eleven contributing factors influencing the efficacy of percutaneous retrogasserian glycerol rhizotomy were identified by logistic regression analysis. Among 210 patients receiving percutaneous retrogasserian glycerol rhizotomy, 67 underwent two procedures and 16 underwent three. Complete pain relief was achieved in 92.4% of patients. The presence of trigger point and painless in the procaine test were the predictors of complete pain relief. Painless in the procaine test is essential to achieve complete pain relief for patients with definite trigger points. Percutaneous retrogasserian glycerol rhizotomy is a minimally invasive, safe, and effective therapeutic strategy for trigeminal neuralgia patients. There are no adverse events or only few complications after surgery. A second injection may be effective for recurrent patients and those unresponsive to initial treatment.

Key words: Trigeminal neuralgia, percutaneous retrogasserian glycerol rhizotomy, logistic regression analysis.