African Journal of Immunology Research

African Journal of Immunology Research ISSN 9431-5833 Vol. 7 (3), pp. 001-005, March, 2020. © International Scholars Journals

Full Length Research Paper

Effects of immune synergist of Chinese medicinal herbs on the efficacy of vaccination against classic swine fever

Fuchuan Wang1, Yibo Yan1*, Yuhuan Zhang1, Yichao Han1 and Chao Guan2

1Institute of Animal Husbandry and Veterinary Sciences, Shanxi Academy of Agricultural Sciences, Taiyuan 030032, China.

2Modern Agricultural Research Center, Taiyuan 030000, China.

Accepted 22 October, 2019

Abstract

Two-month-old piglets were fed with 1, 1.5 and 2% immune synergist of Chinese medicinal herbs together with vaccination against classic swine fever. Serum IgG and IgM levels increased more than the control group on day 30 (P<0.05). B and T lymphocyte proliferation in piglets fed with 1.5 and 2% herbal immune synergist markedly increased on day 30 as compared to the control group (P<0.05). Improvement was also observed in T lymphocyte CD3+, CD4+, CD8+ and CD3+/CD8+ levels. Meanwhile, there were significant differences in SOD activities and rate of neutrophil phagocytosis between synergist groups and the control group. These results suggest that herbal immune synergist of Chinese traditional herbs prescription enhances the protective effect of classic swine fever vaccine.

Key words: Immune synergist, Chinese medicinal herbs, classic swine fever vaccine.